What is L-Histidine HCL, and do I need it?
Histidine is one of the 23 amino acids used to build proteins in humans, known chemically as proteinogenic amino acids. It uses the codons cytosine-adenine-uracil (CAU) and cytosine-adenine-cytosine (CAC). The German physician Albrecht Kossel first isolated histidine in 1896. It was first believed to be an essential amino acid only in infants, although subsequent research has now established histidine as an essential amino acid for all humans.
Humans can biosynthesize small amounts of histidine in the form of 3-methyl histidine. However, this quantity is insufficient to meet the body’s requirements for histidine. The primary dietary sources of histidine are animal protein, including meat, eggs and dairy products. The best plant-based sources of histidine include grains such as rice, rye and wheat. Additional vegetable with significant histidine levels include beans, buckwheat, cauliflower and potatoes. L-histidine is often sold in pure form, commonly known as L-histidine base, for use as a health supplement.
An imidazole functional group is one of histidine’s defining characteristics and accounts for many of its biochemical effects. This group serves as a catalytic site for some enzymes, and it is also commonly used in biosynthesis of metalloproteins. Histidine is also frequently used to activate amino acids such as cysteine, serine and threonine as nucleophiles.
L-histidine HCL is commonly used in health supplements to aid with inflammation management. It is also used to support the digestive system and provide antioxidant activity.
A low hemoglobin level and red blood cell count are some of the most common signs of a low L-histidine level. An L-histidine deficiency is also associated with age-related joint conditions, including stiffness and discomfort. Additional signs that you may need L-histidine supplements include nerve deafness and an imbalance of intestinal flora. You may also need L-histidine if you suffer from oxidative stress, which often causes visible signs of aging.
One of the most common uses of L-histidine as a health supplement is for the support of joint function. It is also used to support seasonal conditions and the nervous system. Blood production may also be a benefit of this supplements.
L-histidine does a ton for your body. It helps with the digestive system, supports the production of growth of the myelin sheaths around nerve cells, helps with your joints, and may even help to remove heavy metals such as zinc from your body. If you have any of the symptoms above, you may want to start using more L-histidine.